If you are over 70 and 1/2 or have inherited an IRA you need to take a required minimum distribution (RMD) before year end.
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The RMD rules apply to all employer sponsored retirement plans, including
profit-sharing plans, 401(k) plans, 403(b) plans, and 457(b) plans. The RMD rules also apply to traditional IRAs and IRA-based plans such as SEPs, SARSEPs, and SIMPLE IRAs.
The RMD rules also apply to Roth 401(k) accounts. However, the RMD rules do not apply to Roth IRAs while the owner is alive. (Source: IRS)
Failure to take the RMD before year-end will result in a 50% tax.